Hepatitis B Vaccination is the most effective prevention method. The complete course of vaccination takes a total of three injections. The second injection is given 1 month after the first, and the third injection 5 months after the second. About 90 to 95% of people will gain life-long immunity to hepatitis B after a full course of vaccination. Preferably have blood tests before vaccinated. Only people who have never been exposed to hepatitis B should have vaccination. Hepatitis B Vaccination is recommended for newborn, household and sexual contacts of chronic hepatitis B, intravenous drug users, people who receive blood or blood products on a regular basis, people on dialysis and health care workers who might be in contact with blood or other body fluids.